Polyethylene glycol cetyl ether (polyethylene glycol hexadecyl ether) is a nonionic surfactant produced by the ethoxylation of cetyl alcohol to give a material with the general formula HO(C₂H₄O)_nC₁₆H₃₃. Several grades of this material are available depending on the level of ethoxylation performed, with repeat units (n) of polyethylene glycol varying between 2 and 20. Commercially it can be known as Cetomacrogol 1000, Brij 58 (when n=20), Brij 56 (when n=10), and other trade names.

It is used as a solubilizer and emulsifying agent in foods, cosmetics, and pharmaceuticals, often as an ointment base.^[1] It is used as an oil in water (O/W) emulsifier for creams/lotions, and a wetting agent.

• Isoceteth-20 - a similar material made using iso-cetyl alcohol