Calle Ocho is Spanish for Eighth Street, and is a street in Miami that is part of the Tamiami Trail.
It can also refer to:
- Calle Ocho Festival, a street fair in Miami
- "I Know You Want Me (Calle Ocho)", a 2008 song by Pitbull
- Little Havana, a Cuban-American neighborhood in Miami centered around Calle Ocho
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