CNC typically refers to computer numerical control, the automated control of machining tools by computer.

CNC or cnc may also refer to:

• China Netcom, a Chinese telecommunications provider
• China Xinhua News Network Corporation, state-run television news channel in China aimed at a foreign audience
• Community Newspaper Company, a former Massachusetts newspaper chain now part of GateHouse Media

• Cadet Nurse Corps, a World War II-era United States government program to train nurses
• Cantabrian Nationalist Council, a nationalist/left-wing party in Cantabria, Spain
• Centre national du cinéma et de l'image animée, a cinema regulatory agency under the French Ministry of Culture
• Ceylon National Congress, a former political party in Ceylon
• Civil Nuclear Constabulary, a UK police force that guards nuclear installations
• National Congress of the Canaries, known in Spanish as Congreso Nacional de Canarias

• Centre for Neuroscience and Cell Biology, a bioscience and biomedicine research institute of the University of Coimbra
• Colegio Nacional de la Capital, a public high school in Asuncion, Paraguay
• College of New Caledonia, a post-secondary educational institution that serves the residents of the Central Interior of British Columbia
• Chippewa Nature Center, a private non-profit educational facility in Midland, Michigan

• Haas CNC Racing, the original name of Stewart Haas Racing
• Collegiate National Championship (disambiguation)

• Cancer (constellation), astronomical constellation (IAU abbreviation Cnc)
• City Nature Challenge, an urban bioblitz competition
• Configurable Network Computing, a JD Edwards client-server architecture
• Consensual non-consent, a BDSM practice
• Crown Nominations Commission, a body involved in the appointment of Church of England bishops
• Czech National Corpus, a corpus of Czech language
• Coconut Island Airport, IATA airport code "CNC"

• C&C (disambiguation)