CMV423 (2-chloro-3-pyridin-3-yl-5,6,7,8-tetrahydroindolizine-1-carboxamide) is an experimental antiviral drug that has been studied for the treatment of cytomegalovirus (CMV) infection[1] and human herpesvirus 6 (HHV-6) infection.[2][3] The drug was investigated by Sanofi-Aventis, but its development was discontinued by 2018 before entering clinical trials.[2]

References

  1. ^ Snoeck R, Andrei G, Bodaghi B, Lagneaux L, Daelemans D, de Clercq E, et al. (September 2002). "2-Chloro-3-pyridin-3-yl-5,6,7,8-tetrahydroindolizine-1-carboxamide (CMV423), a new lead compound for the treatment of human cytomegalovirus infections". Antiviral Research. 55 (3): 413–424. doi:10.1016/s0166-3542(02)00074-8. PMID 12206879.
  2. ^ a b "CMV 423". AdisInsight. Springer Nature Switzerland AG.
  3. ^ Aoki FY (2015). "45 - Antivirals against Herpes Viruses". In Bennett JE, Blaser MJ, Dolin R (eds.). Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases (8th ed.). pp. 546–562. doi:10.1016/B978-1-4557-4801-3.00045-X. ISBN 978-1-4557-4801-3.
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