Bus is a nickname, notable users of which include:

• Bus Griffiths (1913-2006), cartoonist, lumberjack, and fisherman
• Bus Mertes (1921–2002), American football player and coach
• Bus Whitehead (1928–2010), American basketball player
• Bus Wilbert (1915–1946), American racecar driver
• Bus Cook, National Football League sports agent
• Harry "Bus" Yourell (1919–2011), American politician
• Jerome Bettis, "the Bus," (1972–), National Football League player

• The Bus (disambiguation)
• Bus (surname)