Bonilla is a surname of Spanish origin. It may refer to:

• Alejandro Bonilla (1820-1901), Dominican painter and teacher
• Andrea Bonilla (born 1978), Bolivian politician
• Andrea Bonilla (runner) (born 1986), Ecuadorian long-distance runner
• Armando Bonilla (born 1967), American attorney who is a Judge of the U.S. Court of Federal Claims
• Arturo Bonilla (born 1953), Honduran footballer
• Bobby Bonilla (born 1963), American baseball player who played from 1986 to 2001 in Major League Baseball
• Breyner Bonilla (born 1986), Colombian footballer
• Byron Bonilla (born 1993), Nicaraguan footballer
• Charles F. Bonilla (1909–1987), American chemist
• Cristian Bonilla (born 1993), Colombian footballer
• Daryl Bonilla (born 1975), Hawaiian actor, comedian, and professional wrestler.
• E. J. Bonilla (born 1988), American actor
• Fernando Bonilla (born 1962), Puerto Rican politician who served as Secretary of State of the Commonwealth of Puerto Rico
• Gerardo Bonilla – Professional race car driver.
• Giselle Bonilla (born 1994), American actress.
• Héctor Bonilla (1939–2022), Mexican actor
• Henry Bonilla – Former Congressman who represented Texas's 23rd congressional district in the U.S. House of Representatives.
• Hugo Orellana Bonilla – Peruvian painter.
• Jaime Bonilla Valdez (born 1950), Mexican politician and entrepreneur who served as Governor of Baja California from 2019 to 2021
• Jaime Antonio “Jimmy” Bonilla Santiago, Puerto Rican Salsa and Tropical Music Singer. Profesor and Retired US Army.
• Javi Bonilla (born 1990), Spanish footballer
• Jesús Bonilla (born 1955), Spanish actor
• Joaquín Díaz Bonilla (born 1989), Argentine rugby union player
• José Bonilla, Mexican astronomer who in 1883 took the earliest known photograph of an unidentified flying object, the Bonilla Observation
• Jose Bonilla (boxer) (1967–2002), Venezuelan boxer and former world champion
• José Eulogio Bonilla (born 1946), Mexican politician, senator
• José María Bonilla (1889–1957), Guatemalan writer
• José Santiago de Bonilla y Laya-Bolívar (1756–1824), Costa Rican politician
• Juan Bonilla (baseball) (born 1955), Puerto Rican baseball player
• Juan Bonilla (bishop) (1636–1696), bishop of Ariano, 1689–96
• Juan Bonilla (writer) (born 1966), Spanish writer
• Juan Crisóstomo Bonilla (1835–1884), Mexican general
• Juan José de Bonilla y Herdocia (1790–1847), Costa Rican politician
• Leonor Bonilla (born 1970), Mexican actress
• Leydy Bonilla – Dominican singer
• Lisalverto Bonilla – Dominican baseball pitcher
• Manuel Bonilla – President of Honduras from 1903 to 1907 and from 1912 to 1913
• Manuel Bonilla Elhart – Peruvian war hero
  • Manuel Bonilla Sports Complex
• Marc Bonilla (born 1955), American guitarist.
• Nelson Bonilla (born 1990), Salvadoran footballer
• Olivia Bonilla (born 1992), American singer-songwriter and musician
• Óscar Bonilla (born 1978), Honduran footballer
• Pablo Bonilla (born 1999), Venezuelan footballer
• Policarpo Bonilla (1858–1926), President of Honduras from 1894 to 1899.
• Socorro Bonilla (born 1947), Mexican actress
• Susan Bonilla (born 1960), American politician who served in the California State Assembly
• Víctor Bonilla (born 1971), Colombian footballer
• Yarimar Bonilla (born 1975), Puerto Rican political anthropologist

• Ignacio Bonillas – Mexican diplomat and former Mexican ambassador of the United States of America.
• Iñaki Bonillas – Mexican artist.
• Alfonso Bonilla Aragón International Airport – Airport in Cali, Colombia.
• Bonilla, South Dakota
• Juan C. Bonilla (municipality), a municipality in Puebla, Mexico
• Lake Bonilla, Costa Rica