Bianco is an Italian surname meaning "white". Notable people with the surname include:

• Adriana Bianco (born 1941), known professionally as Adrianita, Argentine actress
• Alessandro Bianco (born 2002), Italian footballer
• Andrea Bianco, Italian sailor and cartographer of the 15th century
• Bartolommeo Bianco (1604–1656), Italian architect and painter
• Caroline Blanco (pastor) (1949–2010), French pastor
• Chris Bianco (born 1960), American celebrity chef
• Enzo Bianco (born 1951), Italian politician
• Esmé Bianco (born 1982), British actress, model, and performer
• Eugene "Bianco" Bianco (1927–2007), American harpist
• Gino Bianco (1916–1984), Italian racing driver
• Lory Bianco (born 1963), American singer
• Lucio Bianco (born 1941), Italian engineer
• Lucien Bianco (born 1930), French historian
• Margery Williams Bianco (1881–1944), English-American author
• Mike Bianco (born 1967), American baseball coach
• Nicholas Bianco (1932–1994), New York mobster
• Raffaele Bianco (born 1987), Italian footballer
• Umberto Zanotti Bianco (1889–1963), Italian archaeologist and politician

• Eleonora Lo Bianco (born 1979), Italian volleyball player
• Tony Lo Bianco (born 1936), American actor