Aisha (Arabic: عائشة, romanized: ʿĀʾisha; c. 613–678), was the third wife of Muhammad.

Aisha or variant spellings may also refer to:

• Aisha (1953 film), an Egyptian drama
• Aisha (2010 film), an Indian romantic comedy-drama, an adaptation Jane Austen's Emma
• Aisha (2022 film), an Irish drama
• Aayisha, a 1964 Indian Malayalam film
• Ayisha (film), a 2023 Indian film

• "Aisha", a song by John Coltrane from the 1961 album Olé Coltrane
• "Aisha", a 1999 song by Death in Vegas
• "Aïcha", a 1996 song by Khaled
• "Aïcha", a 2003 song by Singuila
• "Ayesha", a 2019 song by Cupcakke

• Ayesha (novel), by H. Rider Haggard, 1905, a sequel to She
  • The titular character of both novels is also named Ayesha.
• Aisha (TV series), a Maldivian television series
• A.I.SHA My Virtual Girlfriend, an Indian TV series
• Kismet (Marvel Comics), a fictional character also known as Ayesha
• Aisha, a character from the Italian animated series Winx Club
• Aisha Banerjee, fictional character in the 2009 Indian film Wake Up Sid, played by Konkona Sen Sharma
• Ayesha, fictional character in the 2014 Indian film Ek Villain, played by Shraddha Kapoor

• Aisha (given name), an Arabic female given name, including a list of people and fictional characters with the name
• Aisha (Latvian singer) (Aija Andrejeva, born 1986)
• Aisha (poet) (ʿĀʾisha bint Aḥmad al-Qurṭubiyya), a 10th-century poet
• Aisha (reggae singer) (Pamela Ross, born 1962), a British singer
• Aishah (singer) (Wan Aishah binti Wan Ariffin, born 1965), a Malaysian singer and politician
• Aisha (아샤), member of South Korean girl group Everglow

• Ayesha (woreda), Ethiopia
  • Aysha, Ethiopia is a town located in the woreda
• Ayesha River, Ethiopia

• Ayesha (cicada), a genus of cicadas
• Aysha (spider), a genus of spiders
• Ayesha (ship), a wooden topsail schooner, launched 1907
• Aisha Association for Woman and Child Protection
• Ayesha pole move, an advanced pole dance position

• All pages with titles beginning with Aisha
• All pages with titles beginning with Ayesha
• Aysheaia, an extinct genus of fossil organisms