Afovirsen is an oligonucleotide capable of antisense interactions with mRNA of human papillomavirus. It has been investigated as a tool for diagnostics and therapeutics.[1][2]

Nucleic acid sequence

Afovirsen consists of a sequence of 20 nucleic acids

ttgcttccat cttcctcgtc

References

  1. ^ Crooke, RM; Graham, MJ; Cooke, ME; Crooke, ST (October 1995). "In vitro pharmacokinetics of phosphorothioate antisense oligonucleotides". The Journal of Pharmacology and Experimental Therapeutics. 275 (1): 462–73. PMID 7562586.
  2. ^ Liang, H; Nishioka, Y; Reich, C F; Pisetsky, D S; Lipsky, P E (1 September 1996). "Activation of human B cells by phosphorothioate oligodeoxynucleotides". Journal of Clinical Investigation. 98 (5): 1119–1129. doi:10.1172/JCI118894. PMC 507533. PMID 8787674.
Allikas: http://en.wikipedia.org/wiki/Afovirsen
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