In enzymology, an acyl-phosphate-hexose phosphotransferase (EC 2.7.1.61) is an enzyme that catalyzes the chemical reaction

acyl phosphate + D-hexose an acid + D-hexose phosphate

Thus, the two substrates of this enzyme are acyl phosphate and D-hexose, whereas its two products are acid and D-hexose phosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is acyl-phosphate:D-hexose phosphotransferase. This enzyme is also called hexose phosphate:hexose phosphotransferase.

• Anderson RL; Kamel MY (1966). "Acyl phosphate: Hexose phosphotransferase (Hexose phosphate: Hexose phosphotransferase)". Acyl phosphate:hexose phosphotransferase (hexose phosphate:hexose phosphotransferase). Methods Enzymol. Vol. 9. pp. 392–396. doi:10.1016/0076-6879(66)09080-3. ISBN 978-0-12-181809-8.
• Kamel MY, Anderson RL (1967). "Acyl phosphate: hexose phosphotransferase. Purification and properties of the enzyme from Aerobacter aerogenes and evidence for its common identity with hexose phosphate: hexose phosphotransferase". Arch. Biochem. Biophys. 120 (2): 322–31. doi:10.1016/0003-9861(67)90246-9. PMID 6033450.