In enzymology, an acetyl-CoA C-myristoyltransferase (EC 2.3.1.155) is an enzyme that catalyzes the chemical reaction

myristoyl-CoA + acetyl-CoA 3-oxopalmitoyl-CoA + CoA

Thus, the two substrates of this enzyme are myristoyl-CoA and acetyl-CoA, whereas its two products are 3-oxopalmitoyl-CoA and CoA.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is myristoyl-CoA:acetyl-CoA C-myristoyltransferase.

• Miyazawa S, Furuta S, Osumi T, Hashimoto T, Ui N (August 1981). "Properties of peroxisomal 3-ketoacyl-coA thiolase from rat liver". J. Biochem. 90 (2). Tokyo: 511–9. PMID 6117552.

• Eukaryotic Linear Motif resource motif class MOD_NMyristoyl