A New Leaf or New Leaf may refer to:

• "A New Leaf" (short story), by F. Scott Fitzgerald
• A New Leaf (film), a 1971 film
• A New Leaf (TV series), a 2014 South Korean television series
• "New Leaf" (SpongeBob SquarePants), a 2006 episode of SpongeBob SquarePants
• New Leaf (Scheer), a 2007 public artwork by Lisa Scheer
• Animal Crossing: New Leaf, a 2012 video game
• NewLeaf, a former Canadian virtual airline
• New Leaf Market, California-based health food stores bought by New Seasons Market
• A New Leaf (book), a 2004 non-fiction book about cannabis by Alyson Martin and Nushin Rashidian