Guido Andreozzi and Théo Arribagé defeated Rafael Matos and Marcelo Melo in the final, 7–5, 4–6, [10–7] to win the doubles tennis title at the 2025 Argentina Open. It was Arribagé's first ATP Tour doubles title and Andreozzi's second.^[1]

Simone Bolelli and Andrea Vavassori were the reigning champions,^[2] but did not participate this year.

	First round							Quarterfinals							Semifinals							Final
	1	M González A Molteni	63	2
		G Andreozzi T Arribagé	77	6					G Andreozzi T Arribagé	6	6
		L Darderi M Navone	63	77	[10]				L Darderi M Navone	3	1
		D Hidalgo A Tabilo	77	62	[3]											G Andreozzi T Arribagé	6	6
	4	A Erler C Frantzen	6	6											4	A Erler C Frantzen	1	4
	Alt	JP Ficovich M Kestelboim	3	4				4	A Erler C Frantzen	6	7
	WC	A Collarini G Durán	4	3					G Jacq O Luz	4	5
		G Jacq O Luz	6	6																			G Andreozzi T Arribagé	7	4	[10]
	Alt	B Arias F Zeballos	0	2																		3	R Matos M Melo	5	6	[7]
		F Cabral J-J Rojer	6	6					F Cabral J-J Rojer	4	77	[8]
	Alt	L Midón G Villanueva	62	2				3	R Matos M Melo	6	63	[10]
	3	R Matos M Melo	77	6											3	R Matos M Melo	w/o
		D Džumhur D Lajović	7	62	[10]											F Cerúndolo TM Etcheverry
	WC	RA Burruchaga JB Torres	5	77	[8]				D Džumhur D Lajović	63	1
		F Cerúndolo TM Etcheverry	7	6					F Cerúndolo TM Etcheverry	77	6
	2	S Doumbia F Reboul	5	4

• Main draw