The 2022 Orlando USTA Pro Circuit Event was a professional tennis tournament played on outdoor hard courts. It was the third edition of the tournament which was part of the 2022 ITF Women's World Tennis Tour. It took place in Orlando, Florida, United States between 24 and 30 January 2022.^[1]

Country	Player	Rank1	Seed
JPN	Misaki Doi	75	1
CHN	Zheng Qinwen	108	2
MEX	Renata Zarazúa	130	3
CHN	Wang Xiyu	139	4
CHN	Yuan Yue	156	5
USA	CoCo Vandeweghe	161	6
SUI	Leonie Küng	162	7
USA	Hailey Baptiste	165	8

• ¹ Rankings are as of 17 January 2022.

The following players received wildcards into the singles main draw:

• Elvina Kalieva
• Ashlyn Krueger
• Whitney Osuigwe
• Sachia Vickery

The following players received entry from the qualifying draw:

• Sophie Chang
• Catherine Harrison
• Vera Lapko
• Tatjana Maria
• Robin Montgomery
• Sada Nahimana
• Marine Partaud
• Marcela Zacarías

The following players received entry as lucky losers:

• Hsu Chieh-yu
• Danielle Lao

• Zheng Qinwen def. Christina McHale, 6–0, 6–1

• Hailey Baptiste / Whitney Osuigwe def. Angela Kulikov / Rianna Valdes, 7–6^(9–7), 7–5

• 2022 Orlando USTA Pro Circuit Event at ITFtennis.com