The 2022 Internazionali Femminili di Tennis Città di Caserta was a professional tennis tournament played on outdoor clay courts. It was the thirty-third edition of the tournament which was part of the 2022 ITF Women's World Tennis Tour. It took place in Caserta, Italy between 6 and 12 June 2022.^[1]

• Kristina Mladenovic def. Camilla Rosatello, 6–4, 4–6, 7–6^(7–3)

• Despina Papamichail / Camilla Rosatello def. Francisca Jorge / Matilde Jorge, 4–6, 6–2, [10–6]

Country	Player	Rank1	Seed
FRA	Clara Burel	94	1
FRA	Kristina Mladenovic	107	2
	Elina Avanesyan	138	3
GRE	Despina Papamichail	170	4
JPN	Moyuka Uchijima	209	5
SUI	Simona Waltert	211	6
ITA	Federica Di Sarra	212	7
LAT	Daniela Vismane	230	8

• ¹ Rankings are as of 23 May 2022.

The following players received wildcards into the singles main draw:

• Antonia Aragosa
• Nuria Brancaccio
• Melania Delai
• Lisa Pigato

The following players received entry from the qualifying draw:

• Federica Bilardo
• Diletta Cherubini
• Oana Gavrilă
• Zhibek Kulambayeva
• Irene Lavino
• Elena Malõgina
• Matilda Mutavdzic
• Angelica Raggi

• 2022 Internazionali Femminili di Tennis Città di Caserta at ITFtennis.com
• Official website