The 2012 Sarasota Open was a professional tennis tournament played on clay courts. It was the fourth edition of the tournament which was part of the 2012 ATP Challenger Tour. It took place in Sarasota, United States between April 16 and April 22, 2012.

Country	Player	Rank1	Seed
USA	James Blake	74	1
JPN	Go Soeda	77	2
GER	Björn Phau	93	3
CAN	Vasek Pospisil	95	4
ITA	Paolo Lorenzi	96	5
USA	Sam Querrey	103	6
USA	Wayne Odesnik	109	7
ESP	Rubén Ramírez Hidalgo	110	8

• ¹ Rankings are as of April 9, 2012.

The following players received wildcards into the singles main draw:

• James Blake
• Tim Smyczek
• Mac Styslinger
• Rhyne Williams

The following players received entry from the qualifying draw:

• Brian Baker
• Cătălin Gârd
• Michael Lammer
• Nicholas Monroe

• Sam Querrey def. Paolo Lorenzi, 6–1, 6–7^(3–7), 6–3

• Johan Brunström / Izak van der Merwe def. Martin Emmrich / Andreas Siljeström, 6–4, 6–1

• Official Website
• ITF Search Archived 2010-02-12 at the Wayback Machine
• ATP official site