2,3-Methylenedioxymethamphetamine (2,3-MDMA), also known as ORTHO-MDMA, is a positional isomer of the recreational drug 3,4-MDMA (commonly known as Ecstasy or Molly).[1] It is a monoamine transporter (MAT) substrate and inhibitor similarly to 3,4-MDMA.[2] However, while showing similar potency at the norepinephrine transporter (NET), 2,3-MDMA is less potent at the serotonin transporter (SERT).[2] 2,3-MDMA has not been encountered as a recreational or designer drug.[2]

See also

References

  1. ^ Cody JT, Valtier S (2002). "Differentiation of the 2,3-methylenedioxy regioisomer of 3,4-MDMA (ecstasy) by gas chromatography-mass spectrometry". J. Anal. Toxicol. 26 (7): 537–539. doi:10.1093/jat/26.7.537. PMID 12423014.
  2. ^ a b c Montgomery T, Buon C, Eibauer S, Guiry PJ, Keenan AK, McBean GJ (December 2007). "Comparative potencies of 3,4-methylenedioxymethamphetamine (MDMA) analogues as inhibitors of [3H]noradrenaline and [3H]5-HT transport in mammalian cell lines". Br J Pharmacol. 152 (7): 1121–1130. doi:10.1038/sj.bjp.0707473. PMC 2095113. PMID 17891159.



Allikas: http://en.wikipedia.org/wiki/2,3-Methylenedioxymethamphetamine
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