The following lists events that happened during 1841 in South Africa.

Source:^[1]

• Missionary David Livingstone arrives in the Cape Colony and proceeds to Kuruman before journeying through Central Africa.
• Voortrekkers set up a council in Potchefstroom
• Cape Masters and Servants Ordinance is passed, replacing Ordinance 50. It removes racial distinction among servants. White, coloured, and ex-slaves face equal legal penalties if they commit contract breaches.
• Refugees return to Natal, increasing the African population. The Boers see this as a security threat so the Volksraad orders "surplus" Africans, those not working for whites, to relocate between the Mtamvuba and Mzimvubu Rivers.

• 1 May - Sir Rufane Shaw Donkin, acting Governor of the Cape Colony who supervised the arrival and settling of the British settlers and who founded Port Elizabeth, dies in Southampton, England

See Years in South Africa for list of References