The year 1741 in architecture involved some significant events.

• Auberge de Castille in Valletta, Malta, remodelled to a plan attributed to Andrea Belli.
• New building for the Royal Infirmary of Edinburgh in Scotland, designed by William Adam, opens.
• Mineral Water Hospital, Bath, England, designed by John Wood, the Elder, completed
• North Parade, Bath, designed by John Wood, completed about this date.
• Santissimo Nome di Maria al Foro Traiano in Rome, designed by Antoine Derizet, completed about this date.
• Construction begins on the following Palladian style buildings
  • The Berlin Court Opera, to a design by Georg Wenzeslaus von Knobelsdorff.
  • Russborough House in Ireland, to a design by Richard Cassels.
• Construction begins on Hôtel de Ville, Wissembourg

• April 1 – George Dance the Younger, English architect (d. 1825)
• October 3 – Johann Christian von Mannlich, German painter and architect (d. 1822)
• December 16 – Erik Palmstedt, Swedish architect (d. 1803)

• May 3 – Josef Munggenast, Austrian architect (b. 1680)
• October 13 – Jean Aubert, French architect (b. c.1680)