Events from the year 1545 in art.

• 
  da Volterra, Descent from the Cross
• 
  Bronzino, Venus, Cupid, Folly and Time
• 
  Michelangelo, The Conversion of Saul
• 
  Bronzino, Eleanor of Toledo with her son Giovanni

• Bronzino
  • Eleanor of Toledo with her son Giovanni de' Medici
  • Portrait of Cosimo I de' Medici
  • Portrait of Giovanni de' Medici as a Child
  • Venus, Cupid, Folly and Time
• Lucas Cranach the Younger – The Conversion of St. Paul
• Gerlach Flicke – Thomas Cranmer
• Master John – Catherine Parr (approximate date)
• Michelangelo – The Conversion of Saul
• Francesco de' Rossi (Il Salviati) – Triumph of Camillus (fresco for Cosimo I de' Medici in Sala dell'Udienza, Palazzo Vecchio, Florence (completed))
• Titian – some dates approximate
  • Portrait of a Young Englishman
  • Portrait of Lavinia Vecellio
  • Portrait of Pietro Aretino
  • Portrait of Pope Paul III
• Daniele da Volterra (after drawings by Michelangelo) – Descent from the Cross (approximate date)

• (approx. date) – Hans Gieng of Fribourg completes work on the fountains of Bern in Switzerland.

• date unknown
  • Farrukh Beg, Mughal painter who served in the court of Muhammad Hakim (died 1615)
  • Francesco da Urbino, Italian painter (died 1582)
  • Hans Collaert, Flemish engraver and draughtsman (died 1628)
  • Frans Pourbus the Elder, Flemish Renaissance painter primarily of religious and portraits (died 1581)
  • William Rogers, English engraver (died 1604)
  • Marco Vecellio, Italian painter, nephew of Titian (died 1611)
  • Juan Zariñena, Spanish painter (died 1634)

• September - Hans Baldung, German Renaissance artist as painter and printmaker in woodcut (born 1484)
• date unknown
  • Alejo Fernandez, Spanish painter best known for his portrait of Christopher Columbus (born 1475)
  • Rueland Frueauf the Younger - German Late-Gothic painter (born 1470)
  • Albrecht Glockendon the Younger, German miniaturist and woodcutter (born 1500)
  • Vicente Juan Masip - Spanish painter of the Renaissance period (born 1475)
  • Wang E, Chinese landscape painter (born 1465)