Perugia is a city in central Italy, the capital of Umbria.

Perugia may also refer to:

• Cippus of Perugia, a stone tablet bearing an Etruscan inscription
• "From Perugia", a poem by American Quaker poet John Greenleaf Whittier
• Perugia (album), a 1974 jazz album by American pianist Roland Hanna
• Polyptych of Perugia, a Renaissance painting by Italian artist Piero della Francesca

• 151 Infantry Division Perugia, an Italian infantry division of World War II
• Battle of Perugia, an ancient Roman battle

• André Perugia (1893-1977), French shoe designer
• Andrew of Perugia (died c. 1332), Franciscan friar and bishop
• Constantius of Perugia (died c. 170 AD), Christian martyr, bishop, and saint
• Giannicolo da Perugia (c. 1460–1544), Italian painter during the Renaissance
• Herculanus of Perugia (died 549 AD), bishop of Perugia and Christian martyr
• Ilaria Perugia (born 1969), Italian mathematician
• John of Perugia and Peter of Sassoferrato (13th century), Franciscan friars
• Matteo da Perugia (fl. 1400–1416), Medieval Italian composer
• Niccolò da Perugia (fl. 14th century), Italian composer of the "ars nova"
• Paul of Perugia (14th century), Italian mythographer
• Vincenzo Perugia (1881–1925), the man who stole the Mona Lisa

• Duchy of Perugia, a duchy in the Italian part of the Byzantine Empire
• Province of Perugia, Umbria, Italy

• A.C. Perugia Calcio, an Italian football (soccer) club based in Perugia
• Cippus of Perugia, a stone tablet discovered near Perugia, Italy, in 1822
• Perugia Cathedral, Perugia, Italy
• Perugia Press, an American poetry press
• Perugia's limia, a small fish of the family Poeciliidae
• University of Perugia, Perugia, Italy