Nagpal (snake protector) is a Sanskrit origin surname of the Khatri, Arora and Kamboj castes. Notable people with the name include:
- Amitosh Nagpal, Indian film actor, screenwriter and lyricist
- Deepshikha Nagpal (born 1968), Indian actress
- Devendra Nagpal, Indian politician
- Durga Shakti Nagpal (born 1985), Indian civil servant
- Harish Nagpal (born 1964), Indian politician
- Harit Nagpal (born 1961), Indian businessman
- Mahander Nagpal (born 1959), Indian politician
- Nisha Nagpal, Indian television actress
- Nirmala Nagpal, Indian dance choreographer
- Radhika Nagpal, Indian computer scientist
- Rajat Nagpal, Indian singer, composer, producer and mix engineer
- Smriti Nagpal, Indian TV presenter
- Simba Nagpal, Indian actor and model
- Vinod Nagpal, Indian film actor and classical singer
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