Moriarty may refer to:

• Moriarty (name), an Irish surname

• Moriarty, New Mexico, United States, a city
  • Moriarty Air Force Station, a closed United States Air Force radar station
• Mount Moriarty, British Columbia, Canada
• Moriarty, Tasmania, a locality in Tasmania, Australia
• Moriarty Rocks, Tasmania, Australia
• 5048 Moriarty, a main-belt asteroid

• Professor Moriarty, Sherlock Holmes' nemesis
• Jim Moriarty, one of the main antagonists in the British TV series Sherlock
• Jamie Moriarty, aka Irene Adler, in the TV series Elementary
• Moriarty, aka Mira Troy, in the 2022 movie Enola Holmes 2
• Jack Moriarty, in the Holmes-inspired television series House
• Count Jim Moriarty, character in The Goon Show
• Dean Moriarty, in the novel On the Road by Jack Kerouac
• Moriarty, in the 1970 film Kelly's Heroes
• Colin Moriarty, crime boss and owner of Moriarty's Saloon in the video game Fallout 3
• Mark Moriarty, in the 1993 DOS game Eagle Eye Mysteries

• Moriarty (band), a French-American group
• Moriarty (novel), by Anthony Horowitz
• Moriarty (podcast), a mystery drama podcast