Route 287 or Highway 287 may refer to:

• BR-287

• Manitoba Provincial Road 287
• Quebec Route 287

• Japan National Route 287

• Interstate 287
• U.S. Route 287
• Alabama State Route 287
• Arizona State Route 287
• Connecticut Route 287
• Georgia State Route 287 (former)
• Iowa Highway 287 (former)
• Kentucky Route 287
• Maryland Route 287
• Minnesota State Highway 287
• Montana Highway 287
• New York State Route 287 (former)
• Ohio State Route 287
• Pennsylvania Route 287
• Tennessee State Route 287
• Texas State Highway 287 (former proposed)
  • Texas State Highway Loop 287
  • Farm to Market Road 287 (Texas)
• Utah State Route 287
• Virginia State Route 287