The Horton Road Hospital was a mental health facility in Horton Road, Gloucester, England.

The hospital, which was designed by William Stark (who died before the hospital was fully designed),^[1] John Wheeler (who also died before the hospital was fully designed) and John Collingwood using a radial plan layout, opened as the First Gloucestershire County Asylum in July 1823.^[2][3] The west wing was extended in 1846.^[2]

The facility joined the National Health Service as the Horton Road Hospital in 1948.^[2] In the early 1970s the Horton Road Hospital released land on the west of its site to facilitate the construction of the Gloucestershire Royal Hospital.^[2] After the introduction of Care in the Community in the early 1980s, the hospital went into a period of decline and closed in March 1988.^[2] The main building was converted to apartments in 2005.^[2]