Home Sweet Home may refer to:

• Home, Sweet Home (1914 film), a film about the life of John Howard Payne
• Home Sweet Home (1917 film), a British silent film
• Home Sweet Home (1926 film), a silent film drama
• Home, Sweet Home (1933 film), a British film starring Richard Cooper
• Home Sweet Home (1945 film), a British comedy film starring Frank Randle
• Home Sweet Home (1951 film), a Japanese film
• Home Sweet Home (1970 film), a Taiwanese film awarded a Golden Horse Award for Best Feature Film
• Home Sweet Home (1973 film), a Belgian film directed by Benoît Lamy
• Home Sweet Home (1981 film), a slasher film starring Jake Steinfeld
• Home Sweet Home (1982 film), a Mike Leigh television film
• Home Sweet Home (2005 film), a Hong Kong horror film
• Hanasaku Iroha: The Movie – Home Sweet Home, a 2013 Japanese animated film
• Home Sweet Home (2013 film), a horror film starring Meghan Heffern
• Home Sweet Home (2014 film), an Indian Konkani language comedy film
• Home Sweet Home 2, a 2015 Indian Konkani language film
• Home Sweet Home (2016 film), a Kosovan film
• Home Sweet Home Alone, a 2021 American Christmas comedy film

• Home Sweet Home Records

• "Home! Sweet Home!", an 1823 song by Henry Bishop and John Howard Payne
• "Home Sweet Home" (G-Dragon song), 2024
• "Home Sweet Home" (Mötley Crüe song), 1985
• "Home Sweet Home" (The Farm song), 2011
• "Home Sweet Home" (Dennis Robbins song), 1992
• "Home Sweet Home", a song by Yuki

• Home Sweet Home (Kano album)
• Home Sweet Home (Katherine Jenkins album), 2014
• Home Sweet Home, a 1970 solo album by American singer-songwriter Terry Manning
• Home Sweet Home, a 1993 album by American hip-hop group House of Krazees

• Home Sweet Home (Australian TV series), a 1980 Australian sitcom
• Home Sweet Home (2010 TV series), a 2010 South Korean drama
• Home Sweet Home (2013 TV series), a 2013 Philippine drama
• Home Sweet Home (American TV series), a 2021 America reality social experiment series
• Home Sweet Home (Ghanaian TV series), an English-language Ghanaian family television drama series
• "Home Sweet Home" (The Walking Dead), a 2021 episode of The Walking Dead
• "Home Sweet Home" (The Good Life), a 1976 British sitcom episode
• "Home Sweet Home", an episode of the TV series Alvin and the Chipmunks
• Home Sweet Home (Entourage), an episode of the TV series Entourage

• Home Sweet Home (2007 video game), a 2007/2008 game for PC and WiiWare
• Home Sweet Home (2017 video game), a 2017 horror game
• Home Sweet Home (museum), a historic house and museum in East Hampton Village District, New York
• Home Sweet Home, a novel by Jeanne Betancourt
• H2S (radar)

• "Home Sweet Home/Bittersweet Symphony", a 2005 medley by Limp Bizkit
• Home Sweet Homer (musical), a notorious Broadway flop
• "Home Sweet Homeless", an episode of the TV series The Care Bears
• "Home Sweet Homes", an episode of the TV series Barney & Friends