Florescu is a Romanian surname. Notable people with the surname include:

• Alexandru Emanoil Florescu (1822–1907), Romanian politician
• Bonifaciu Florescu (1848–1899), Romanian polygraph and politician
• Gheorghe Florescu (born 1984), Romanian footballer
• Ion Emanuel Florescu (1819–1893), general and Prime Minister of Romania
• Radu Florescu (1925–2014), Romanian historian
• Stefan Florescu (1926/1927–2010), American paralympic swimmer and table tennis player
• Victor Florescu (born 1973), Moldovan judoka

• Florea (name)
• Florești (disambiguation)