Chaulmoogric acid is a fatty acid found chaulmoogra oil, the oil from the seeds of Hydnocarpus wightianus.[2] It is an unusual fatty acid which has a cyclopentene ring at its terminus instead of being entirely linear like most fatty acids.[3]

It is a white crystalline solid with a melting point of 68.5 °C.[1] It is soluble in ether, chloroform, and ethyl acetate.[1]

In the early 20th century, it was investigated as a possible treatment for leprosy due to the use in traditional medicine of chaulmoogra oil for leprosy.[4]

See also

References

  1. ^ a b c The Merck Index (11th ed.). 2037. Chaulmoogric acid.
  2. ^ Sengupta, A.; Gupta, J. K.; Dutta, J.; Ghosh, A. (1973). "The component fatty acids of chaulmoogra oil". Journal of the Science of Food and Agriculture. 24 (6): 669–74. Bibcode:1973JSFA...24..669S. doi:10.1002/jsfa.2740240606. PMID 4737104.
  3. ^ Mislow, Kurt; Steinberg, I. V. (1955). "The Synthesis and Stereochemistry of Chaulmoogric Acid". Journal of the American Chemical Society. 77 (14): 3807–3810. doi:10.1021/ja01619a038.
  4. ^ Ernest Linwood Walker, Marion A. Sweeney (1920). "The Chemotherapeutics of the Chaulmoogric Acid Series and Other Fatty Acids in Leprosy and Tuberculosis : I. Backtericidal Action; Active Principle; Specificity" (PDF). The Journal of Infectious Diseases. 26 (3): 238–264. doi:10.1093/infdis/26.3.238. JSTOR 30084434.
Allikas: Https://en.wikipedia.org/wiki/Chaulmoogric_acid
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