CSR may refer to:

• Central serous retinopathy, a visual impairment
• Cheyne–Stokes respiration, an abnormal respiration pattern
• Child sex ratio, ratio between female and male births
• Class switch recombination, a process that changes the constant region of an immunoglobulin
• Clinical study report, on a clinical trial
• Combat stress reaction, a condition also known as shell shock or battle fatigue
• C-S-R Triangle theory, an application of the universal adaptive strategy theory to plant biology in which strategies are competitor, stress tolerator, and ruderal

• Certificate signing request, in computer security
• Command success rate, a measure of performance in computer speech recognition programs
• Compressed sparse row, a storage format for a sparse matrix
• Control/Status Register, a register in central processing units

• Chinese Soviet Republic, a short-lived state in 20th century China
• Common Sense Revolution, a political movement in Ontario, Canada
• Community service register, a type of police report in India
• Comprehensive School Reform, a program administered by the U.S. Department of Education
• Comprehensive Spending Review, a governmental process in the United Kingdom carried out by HM Treasury
• Cost sharing reductions subsidy, until its elimination in 2017, a primary component of high-deductible health plans under the U.S. Patient Protection and Affordable Care Act (often referred to as Obamacare)
• Czechoslovak Republic, several historical states in Europe

• Center for Scientific Review, a center at the National Institutes of Health, US Department of Health and Human Services
• Centre for Software Reliability, UK
• Center for Strategic Research (Iran), a research governmental institute in Iran
• Comités syndicalistes révolutionnaires, a former a trade-unionist organization
• CSR plc, formerly Cambridge Silicon Radio, a British silicon chip designer and software company
• CSR Corporation Limited, a former Chinese manufacturer of locomotive and rolling stock
• CSR Group, a Chinese railway equipment manufacturer
• CSR Limited, an Australian industrial company, formerly known as Colonial Sugar Refining Company
• Cutch State Railway, a former Indian railway company

• Cognitive science of religion, the study of religious thought and behavior from the perspective of the cognitive and evolutionary sciences
• Cultic Studies Review, a journal on cults, psychology, and religion

• CSR 97.4FM, a radio station in Canterbury, UK
• CSR Racing, a 2012 drag racing game for mobile platforms
• CSR (group), a South Korean girl group
• Team 18, an Australian V8 Supercar team
• C Sports Racer, a class of racing cars
• Cab Secure Radio, a radio telephone system used on UK railways
• C. S. R. Anjaneyulu (1907–1963), an Indian actor
• Canning Stock Route, the longest historic livestock route in the world
• Corn Suitability Rating, a measure of soil quality commonly used in the state of Iowa, US
• Certified shorthand reporter, a court reporter
• Customer service representative, a job title in the service industry
• Cherokee Scout Reservation, a Boy Scout camp in Caswell County, North Carolina
• Cedarlands Scout Reservation, a Boy Scout camp in Long Lake, New York
• Competition Success Review, a youth magazine published in India
• Corporate social responsibility, a concept whereby businesses take responsibility for the impact of their activities
• Complete spatial randomness
• Czechoslovak Socialist Republic, which broke up in 1990