Buffalo River may refer to:
Australia
Canada
- Buffalo River (Alberta), tributary of the Peace River
South Africa
- Buffalo River (Eastern Cape)
- Buffalo River (KwaZulu-Natal)
- Buffalo River (Groot River), Southern Cape
United States
- Buffalo National River, Arkansas
- Buffalo River (Georgia)
- Buffalo River (Minnesota)
- Buffalo River (New York)
- Buffalo River (Tennessee)
- Buffalo Bayou in Houston, Texas
- Buffalo River (Virginia)
- Buffalo River (Wisconsin)
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