Al-Khatib (Arabic: الخطيب) is a surname. People with the surname include:
Surname
- Abdelkrim al-Khatib (1921–2008), Moroccan surgeon, politician and activist
- Ahmad al-Khatib (1933–1982), Syrian politician
- Ahmed Fouad Alkhatib (born 1990 or 1991), Palestinian American activist
- Basil Al-Khatib (born 1962), Syrian director
- Bassam Al-Khatib (born 1975), Jordanian professional footballer
- Firas Al-Khatib (born 1983), Syrian footballer
- Ibtihal Al-Khatib (born 1972), Kuwaiti academic, journalist, and activist
- Ibn al-Khatib (1313–1374), Arab historical figure
- Iyad Mohammad al-Khatib, Syrian politician
- Mahmoud El Khatib (born 1954), Egyptian retired footballer
- Muhammad Mukhtar Al-Khatib (born 1942), Sudanese communist
- Muhammad Nabil Al Khatib, Syrian politician
- Muhib Al Din Al Khatib (1886–1969), Syrian journalist and politician
- Ruhi al-Khatib (1914–1994), Mayor of Jerusalem
- Zaki al-Khatib (1887–1961), Syrian politician
- Abdulrahman Khatib 1996 , Syrian, Youngest CEO of a cybersecurity company
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