Agus may refer to:

• Agus Salim (1884–1954), Indonesian diplomat, foreign minister of Indonesia
• Agus Suhartono (born 1955), Indonesian admiral, commander of Indonesian military forces
• Agus Martowardojo (born 1956), Indonesian economist and politician, finance minister of Indonesia
• Agus R. Sarjono (born 1962), Indonesian writer
• Agus Gumiwang Kartasasmita (born 1969), Indonesian politician, industry minister of Indonesia
• Agus Kuncoro (born 1972), Indonesian actor
• Agus Harimurti Yudhoyono (born 1978), Indonesian politician and former military officer, son of 6th Indonesian president Susilo Bambang Yudhoyono
• Agus Firmansyah (born 1980), Indonesian footballer
• Agus Cima (born 1983), Indonesian footballer
• Agus Prayogo (born 1985), Indonesian runner
• Agus Suhendra (born 1988), Indonesian footballer
• Agus Adi Prayoko (born 1989), Indonesian artistic gymnast
• Agus Durmaturia (born 1992), Indonesian footballer

• Agus (footballer) (born 1985), Spanish footballer
• Agus Medina (born 1994), Spanish footballer

• Agus Padilla (born 2001), Uruguayan singer
• Agus Bernasconi (born 1996), Argentine actor and singer

• Arlene Agus (1949–2024), American Orthodox Jewish feminist and activist
• David Agus (born 1965), American physician
• Jacob B. Agus (1911–1986), American rabbi and theologian

• Gianni Agus (1917–1994), Italian actor
• Zaharah Agus (1922–1978), Malaysian singer

• Agus River, in the Philippines
• Atypical glandular cells of undetermined significance