Andre Agassi defeated Michael Stich in the final, 6–1, 7–6^(7–5), 7–5 to win the men's singles tennis title at the 1994 US Open. It was his first US Open title and second major title overall. Agassi was the first unseeded player to win the title in the Open Era, and the first overall since Fred Stolle in 1966.

Pete Sampras was the defending champion, but lost in the fourth round to Jaime Yzaga.

This tournament marked the final professional appearance of former world No. 1 and eight-time major champion Ivan Lendl; he was defeated in the second round by Bernd Karbacher.

The seeded players are listed below. Andre Agassi is the champion; others show the round in which they were eliminated.

• Q = Qualifier
• WC = Wild card
• LL = Lucky loser
• r = Retired

	Quarterfinals									Semifinals									Final
		Jaime Yzaga	2	79	1	7	3
		Karel Nováček	6	67	6	5	6
											Karel Nováček	5	3	64
										4	Michael Stich	7	6	77
	4	Michael Stich	6	6	67	6
		Jonas Björkman	4	4	79	4
																			4	Michael Stich	1	65	5
																				Andre Agassi	6	77	7
		Andre Agassi	77	6	6
	13	Thomas Muster	65	3	0
											Andre Agassi	6	4	6	6
										9	Todd Martin	3	6	2	3
	9	Todd Martin	6	77	4	6
		Bernd Karbacher	4	65	6	4

	First round									Second round									Third round									Fourth round
	1	P Sampras	6	6	6
	Q	K Ullyett	2	2	2					1	P Sampras	6	6	6
		D Vacek	65	7	6	6					D Vacek	3	4	4
		Y El Aynaoui	77	5	1	1													1	P Sampras	4	6	6	6
		G Rusedski	3	2	6	5													Q	R Smith	6	2	4	3
		H Holm	6	6	3	7					H Holm	3	6	6	1	2
		D Nargiso	64	4	0					Q	R Smith	6	1	3	6	6
	Q	R Smith	77	6	6																							1	P Sampras	6	3	6	64	5
		W Masur	2	6	5	1																							J Yzaga	3	6	4	77	7
	WC	D Witt	6	3	7	6				WC	D Witt	1	77	4	4
		J Yzaga	77	6	6						J Yzaga	6	61	6	6
		G Markus	64	2	2															J Yzaga	1	5	7	6	6
		R Gilbert	6	6	63	2	7													C Pioline	6	7	5	1	4
		M Hadad	4	2	77	6	6				R Gilbert	6	3	64	3
		C Pioline	6	7	4	6					C Pioline	2	6	77	6
	LL	O Gross	2	5	6	4

	First round									Second round									Third round									Fourth round
	10	A Berasategui	1	6	3	3
		M Ondruska	6	2	6	6					M Ondruska	77	6	6
	WC	T Ho	3	3	61						C Bergström	63	3	0
		C Bergström	6	6	77															M Ondruska	3	1	77	6	4
	Q	T El Sawy	64	6	4	2														J Frana	6	6	63	3	6
	WC	V Spadea	77	4	6	6				WC	V Spadea	4	1	6	5
		J Frana	6	1	4	77	6				J Frana	6	6	0	7
	WC	M Merklein	4	6	6	63	0																						J Frana	3	3	77	3
		K Kučera	4	63	3																								K Nováček	6	6	63	6
		M Petchey	6	77	6						M Petchey	3	2	4
	Q	P Kilderry	2	5	2					Q	T Woodbridge	6	6	6
	Q	T Woodbridge	6	7	6														Q	T Woodbridge	6	7	66	2	63
		A Volkov	2	6	1	5														K Nováček	1	5	78	6	77
		K Nováček	6	3	6	7					K Nováček	6	6	6
		G Schaller	3	4	0					8	A Medvedev	3	2	2
	8	A Medvedev	6	6	6

	First round									Second round									Third round									Fourth round
	4	M Stich	77	6	6
		O Delaître	63	3	3					4	M Stich	6	6	6
		F Davín	0	1	1						S Bryan	1	4	2
		S Bryan	6	6	6														4	M Stich	77	6	6
		F Clavet	6	4	6	79														B Black	65	2	1
		J-P Fleurian	3	6	3	67					F Clavet	5	6	6	1	4
		P McEnroe	67	2	4						B Black	7	1	3	6	6
		B Black	79	6	6																							4	M Stich	710	6	6
		J Siemerink	62	4	77	710	4																					14	Y Kafelnikov	68	3	2
		R Krajicek	77	6	62	68	6				R Krajicek	6	63	3	6	64
	Q	N Pereira	6	5	4	7	4				C Costa	4	77	6	1	77
		C Costa	4	7	6	5	6													C Costa	3	4	2
		F Meligeni	2	3	6	4													14	Y Kafelnikov	6	6	6
		M Damm	6	6	4	6					M Damm	3	65	65
		J Eltingh	64	5	3					14	Y Kafelnikov	6	77	77
	14	Y Kafelnikov	77	7	6

	First round									Second round									Third round									Fourth round
	11	J Courier	6	6	6
		A Krickstein	3	4	4					11	J Courier	5	2	6	3
		A Gaudenzi	77	6	77						A Gaudenzi	7	6	3	6
	Q	A Chang	63	1	62															A Gaudenzi	4	1	3
		A Costa	1	5	2															J Renzenbrink	6	6	6
		K Alami	6	7	6						K Alami	3	4	79	3
		J Renzenbrink	6	6	6						J Renzenbrink	6	6	67	6
		G Stafford	1	4	4																								J Renzenbrink	6	3	2	77	3
		P Haarhuis	3	61	3																								J Björkman	3	6	6	63	6
		A O'Brien	6	77	6						A O'Brien	2	3	4
		J Björkman	6	6	7						J Björkman	6	6	6
		J Stark	2	2	5															J Björkman	6	6	6
		J Tarango	4	7	6	3	6												5	S Edberg	4	4	0
	Q	L-A Wahlgren	6	5	4	6	3				J Tarango	2	3	2
		L Jönsson	5	1	1					5	S Edberg	6	6	6
	5	S Edberg	7	6	6

	First round									Second round									Third round									Fourth round
	6	M Chang	6	6	6
		A Cherkasov	4	2	2					6	M Chang	4	6	6	77
		M Washington	65	6	3	6	6				M Washington	6	2	3	63
		K Braasch	77	3	6	3	3												6	M Chang	6	4
		M Larsson	77	7	3	3	3												WC	J Grabb	1	1	r
	WC	J Grabb	62	5	6	6	6			WC	J Grabb	4	6	6	6
	Q	E Ferreira	77	6	6					Q	E Ferreira	6	4	2	3
		A Boetsch	63	4	4																							6	M Chang	1	77	3	6	1
	Q	R Eriksson	3	2	0																								A Agassi	6	63	6	3	6
		A Agassi	6	6	6						A Agassi	6	7	65	6
		G Forget	7	6	6						G Forget	3	5	77	2
	WC	M Wilander	5	1	4															A Agassi	7	6	7
	Q	M Ríos	6	77	6														12	W Ferreira	5	1	5
		J Palmer	2	61	2					Q	M Ríos	4	2	4
	WC	W McGuire	5	2	2					12	W Ferreira	6	6	6
	12	W Ferreira	7	6	6

	First round									Second round									Third round									Fourth round
	13	T Muster	6	6	6
	Q	D Musa	3	2	0					13	T Muster	6	4	6	6
		M Ruah	63	77	6	2	6				M Ruah	4	6	4	2
		J Bates	77	65	4	6	4												13	T Muster	6	6	6
		T Enqvist	4	6	6	65	6													T Enqvist	0	4	2
		À Corretja	6	3	4	77	1				T Enqvist	77	77	64	7
		J Svensson	4	4	2						H Dreekmann	64	62	77	5
		H Dreekmann	6	6	6																							13	T Muster	6	77	6
		B Steven	65	4	6	1																						3	S Bruguera	4	64	4
		M-K Goellner	77	6	3	6					M-K Goellner	77	3
		A Antonitsch	6	77	67	2	3				T Carbonell	64	2	r
		T Carbonell	1	60	79	6	6													M-K Goellner	6	4	2	77	1
		J Stoltenberg	6	6	4	3	4												3	S Bruguera	1	6	6	64	6
		A Olhovskiy	1	4	6	6	6				A Olhovskiy	5	2	65
		B Shelton	0	2	5					3	S Bruguera	7	6	77
	3	S Bruguera	6	6	7

	First round									Second round									Third round									Fourth round
	7	B Becker	1	4	6	6	65
		R Reneberg	6	6	4	1	77				R Reneberg	6	7	6
		J Burillo	6	77	61	6					J Burillo	3	5	3
		K Carlsen	3	64	77	4														R Reneberg	2	6	77	6
		D Wheaton	6	4	2	6	3													R Fromberg	6	1	64	2
		R Fromberg	4	6	6	3	6				R Fromberg	6	6	6
	WC	P Goldstein	4	3	4						R Agénor	3	3	4
		R Agénor	6	6	6																								R Reneberg	6	0	r
		D Rikl	4	1	4																							9	T Martin	3	3
		P Rafter	6	6	6						P Rafter	7	4	712	6
		J Apell	3	6	6	6					J Apell	5	6	610	3
		S Pescosolido	6	3	4	4														P Rafter	5	3	77	2
		A Chesnokov	6	2	77	6													9	T Martin	7	6	63	6
		J Sánchez	3	6	62	2					A Chesnokov	3	2	5
		G Raoux	77	6	3	4	61			9	T Martin	6	6	7
	9	T Martin	64	4	6	6	77

	First round									Second round									Third round									Fourth round
	15	M Rosset	4	1	6	77	6
		M Woodforde	6	6	3	65	3			15	M Rosset	6	6	62	6
		N Kulti	77	2	3	6	6				N Kulti	4	2	77	2
		C Adams	62	6	6	4	4												15	M Rosset	6	4	6	1	2
	Q	L Paes	4	4	2															B Karbacher	4	6	4	6	6
		B Karbacher	6	6	6						B Karbacher	6	77	1
		I Lendl	7	6	6						I Lendl	4	65	0	r
	Q	N Borwick	5	2	3																								B Karbacher	6	4	6	6
	Q	G Pozzi	6	6	6																							Q	G Pozzi	2	6	3	4
		R Furlan	2	4	4					Q	G Pozzi	4	7	3	7	6
		A Mansdorf	6	6	3	6					A Mansdorf	6	5	6	5	3
		E Sánchez	4	4	6	3													Q	G Pozzi	2	6	6	6
	Q	G Doyle	6	2	3	3														M Zoecke	6	4	2	2
		R Weiss	4	6	6	6					R Weiss	1	5	2
		M Zoecke	6	7	3	7					M Zoecke	6	7	6
	2	G Ivanišević	2	5	6	5

• Association of Tennis Professionals (ATP) – 1994 US Open Men's Singles draw
• 1994 US Open – Men's draws and results at the International Tennis Federation