Napoléon is the French form of the Italian given name Napoleone. Notable people with the name include:

• Napoléon Bonaparte (Napoleon I) (1769-1821), French statesman
• Napoléon Charles Bonaparte (1802–1807), prince of Holland and son of Napoleon I's brother Louis
• Napoléon Louis Bonaparte (1804–1831), King of Holland and son of Napoleon I's brother Louis
• Charles Louis Napoléon Bonaparte, Napoleon III (1808-1873), Emperor of the French and son of Napoleon I's brother Louis
• Napoléon François Joseph Charles Bonaparte, Napoleon II (1811-1832), son of Napoleon I
• Napoléon Joseph Charles Paul Bonaparte (1822–1891), son of Napoleon I's brother Jerome
• Napoléon Charles Bonaparte, 5th Prince of Canino (1839–1899), grandson of Napoleon I's brother Lucien

• Napoleón Calzado (born 1977), baseball player from Dominican Republic
• Napoleon Einstein (born 1989), Indian cricketer
• Napoleon Harris (born 1979), American football player
• Napoleon Kaufman (born 1973), American football player
• Napoleon Lajoie (1874–1959), American baseball player
• Napoleon McCallum (born 1963), American football player
• Napoleon Amaefule (born 1980), Nigerian footballer

• Napoleon D'umo (born 1968), American choreographer
• Napoleon Jones-Henderson (born 1943), American weaver and multimedia artist
• Napoleon Murphy Brock (born 1943), American singer and musician
• Napoleon Orda (1807–1883), Belarusian-Polish musician and artist
• Napoleon Perdis (born 1970), Australian make-up artist

• Napoleon Bonaparte Buford (1807–1883), U.S. Army officer and railroad executive
• Napoleon Collins (1814–1875), U.S. Navy admiral
• Napoleon J.T. Dana (1822–1905), U.S. Army officer
• Napoleon Zervas (1891–1957), Greek general
• Napoleone Orsini (1420–1480), Italian warlord

• Napoleon B. Broward (1857–1910), American governor of Florida
• Napoleon Bonaparte Brown (1834–1910), American businessman and politician
• José Napoleón Duarte (1925–1990), President of El Salvador
• Napoleon Wapasha (1854–1925), Sioux chief
• Napoleone della Torre (died 1278), Italian nobleman, Lord of Milan

• Napoleon Bonaparte (born 1965), Indonesian policeman
• Napoleon Cybulski (1854–1919), Polish physiologist
• Napoleon Whiting (1910-1984), American actor
• Napoleon Chagnon (1938–2019), American anthropologist
• Napoleone Orsini Frangipani (1263–1342), Italian cardinal
• Napoleon Hill (1883–1970), American personal-success author
• Napoleon LeBrun (1821–1901), American architect
• Napoléon Peyrat (1809–1881), French author and historian
• Napoléon Coste (1805–1883), French guitarist
• Napoléon Joseph Ney (1803–1857), French politician
• Napoléon La Cécilia (1835–1878), French general
• Napoleone Boni (1863–1927), Italian painter
• Napoleone Nani (1841–1899), Italian painter

• Napoleon "Bony" Bonaparte, a character created by Arthur Upfield
• Napoleon Solo, a character from The Man from U.N.C.L.E.
• Napoleone Di Carlo, a detective created by Italian comic book writer Carlo Ambrosini for the series of the same name published by Sergio Bonelli Editore
• Napoleon Dynamite, the protagonist of the film Napoleon Dynamite
• Muffin, a puppy who calls himself "Napoleon" in the Australian film Napoleon
• Napoleon, the bloodhound from the Disney animated film The Aristocats