The following highways have been numbered 88:

• Picton Road, New South Wales

• Alberta Highway 88
• Ontario Highway 88 (former)

• A88 autoroute

• EO88 road

• National Route 88
• Gukjido 88

• New Zealand State Highway 88

• A88 road, Scotland

• Interstate 88 (Illinois)
  • Interstate 88 (New York)
• Alabama State Route 88
• Arizona State Route 88
• Arkansas Highway 88
• California State Route 88
• Colorado State Highway 88
• Florida State Road 88 (pre-1945) (former)
• Georgia State Route 88
• Illinois Route 88 (former)
  • Illinois Route 88A (former)
• K-88 (Kansas highway)
• Kentucky Route 88
• Louisiana Highway 88
• Maine State Route 88
• Maryland Route 88
• Massachusetts Route 88
• M-88 (Michigan highway)
• Minnesota State Highway 88 (former)
  • County Road 88 (Hennepin County, Minnesota)
  • County Road 88 (Ramsey County, Minnesota)
• Missouri Route 88 (former)
  • Missouri Route 88 (1922) (former)
• Nebraska Highway 88
  • Nebraska Recreation Road 88B
• Nevada State Route 88
• New Hampshire Route 88
• New Jersey Route 88
• New Mexico State Road 88
• New York State Route 88
  • County Route 88 (Cattaraugus County, New York)
  • County Route 88 (Chautauqua County, New York)
  • County Route 88 (Dutchess County, New York)
  • County Route 88 (Monroe County, New York)
  • County Route 88 (Montgomery County, New York)
  • County Route 88 (Oneida County, New York)
  • County Route 88 (Orange County, New York)
  • County Route 88 (Saratoga County, New York)
  • County Route 88 (Steuben County, New York)
  • County Route 88 (Suffolk County, New York)
• North Carolina Highway 88
• Ohio State Route 88
• Oklahoma State Highway 88
• Pennsylvania Route 88
• South Carolina Highway 88
• Tennessee State Route 88
• Texas State Highway 88 (former)
  • Texas State Highway Loop 88 (proposed)
  • Texas State Highway Loop 88 (1939–1990) (former)
  • Farm to Market Road 88
  • Urban Road 88 (signed as Farm to Market Road 88)
• Utah State Route 88
• Virginia State Route 88 (former)
• West Virginia Route 88
• Wisconsin Highway 88

• A88