Fumarprotocetraric acid is a chemical compound with the chemical formula C22H16O12. It is a secondary metabolite produced by a variety of lichens.

Occurrence

Fumarprotocetraric acid is mainly known for its occurrence in Iceland moss (Cetraria islandica), where it is present in a mass fraction of 1–2% (dried thallus).[2]

In addition, fumarprotocetraric acid has been detected in many other lichens, including:

Pharmacology research

Fumarprotocetraric acid has antibacterial activity.[1] It also induces an immunostimulating effect in vitro by triggering the formation of hydrogen peroxide.[1] Furthermore, cytotoxicity against two cancer cell lines has been demonstrated.[1]

References

  1. ^ a b c d e Entry on Fumarprotocetrarsäure. at: Römpp Online. Georg Thieme Verlag, retrieved January 5, 2025.
  2. ^ Egon Stahl, Werner Schild (1986). Isolierung und Charakterisierung von Naturstoffen (1st ed.). Stuttgart/New York: Gustav Fischer Verlag. p. 92.
  3. ^ a b c d e f g h i j k l m Wilhelm Zopf (1907). Die Flechtenstoffe in chemischer, botanischer, pharmakologischer und technischer Beziehung (1st ed.). Gustav Fischer Verlag. pp. 172–176.
  4. ^ a b c d e f g h i j k l m n o p q r s t u v w Emil Abderhalden, ed. (1912), Biochemisches Handlexikon. Gerbstoffe, Flechtenstoffe, Saponine, Bitterstoffe, Terpene, Ätherische Öle, Harze, Kautschuk (1. Auflage ed.), Berlin/Heidelberg: Springer Verlag, pp. 74 f
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