Escherichia coli Nissle 1917 is a strain of Escherichia coli that was isolated from the feces of a German soldier in 1917 by the German researcher Alfred Nissle. Since that time it has been widely studied as a probiotic and several marketed probiotics include it and naturally colonizes the human intestines and has positive probiotic properties.[1] Only 50 to 80% of patients who take it daily have detectable amounts in their feces. The precise reason is unknown. It is known that the F1C fimbriae are important for colonization.[2]

References

  1. ^ Sonnenborn, U (October 2016). "Escherichia coli strain Nissle 1917-from bench to bedside and back: history of a special Escherichia coli strain with probiotic properties". FEMS Microbiology Letters. 363 (19): fnw212. doi:10.1093/femsle/fnw212. PMID 27619890. Open access icon
  2. ^ Lasaro, MA; Salinger, N; Zhang, J; Wang, Y; Zhong, Z; Goulian, M; Zhu, J (January 2009). "F1C fimbriae play an important role in biofilm formation and intestinal colonization by the Escherichia coli commensal strain Nissle 1917". Applied and Environmental Microbiology. 75 (1): 246–51. Bibcode:2009ApEnM..75..246L. doi:10.1128/AEM.01144-08. PMC 2612203. PMID 18997018.
Allikas: https://en.wikipedia.org/wiki/Escherichia_coli_Nissle_1917
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