A60 or A-60 may refer to:

• A60 road, a road connecting Loughborough and Doncaster via Nottingham in England
• A60 highway, a proposed road to connect Valladolid and Leon in Spain
• A60 Highway, a highway which bypasses the southern suburbs of the city of Varese, Italy
• Autobahn 60, a highway in Germany
• Benoni Defense, in the Encyclopaedia of Chess Openings
• Beriev A-60, a Soviet and then Russian airborne laser flying laboratory
• London Underground A60 Stock, rolling stock used on the Metropolitan and East London lines on the London Underground
• Samsung Galaxy A60, smartphone released in 2019
• A model number of the Austin Cambridge car range
• A-series light bulb of diameter 60 mm
• A-60, an entity from Roblox games called DOORS and Rooms