3,5-Difluoro-4-hydroxybenzylidene imidazolinone or DFHBI[2] is an imidazolinone fluorophore used in various biochemical studies. The benzene ring of DFHBI can freely rotate around the single bond but when it is fixed in planar conformation, DFHBI fluoresces.[1] It is a synthetic analog of the GFP fluorophore.

References

  1. ^ a b Dou, Jiayi; Vorobieva, Anastassia A.; Sheffler, William; Doyle, Lindsey A.; Park, Hahnbeom; Bick, Matthew J.; Mao, Binchen; Foight, Glenna W.; Lee, Min Yen; Gagnon, Lauren A.; Carter, Lauren (September 2018). "De novo design of a fluorescence-activating β-barrel". Nature. 561 (7724): 485–491. Bibcode:2018Natur.561..485D. doi:10.1038/s41586-018-0509-0. ISSN 0028-0836. PMC 6275156. PMID 30209393.
  2. ^ a b "DFHBI 1241390-29-3". Sigma Aldrich. Archived from the original on 2022-01-13.


Allikas: https://en.wikipedia.org/wiki/3,5-Difluoro-4-hydroxybenzylidene_imidazolinone
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