The 2012 San Marino CEPU Open was a professional tennis tournament plays on clay courts. It was the 25th edition of the tournament which is part of the Tretorn SERIE+ of the 2012 ATP Challenger Tour. It takes place in City of San Marino, San Marino between 6 and 12 August 2012.

Country	Player	Rank1	Seed
SVK	Martin Kližan	52	1
SLO	Blaž Kavčič	76	2
ITA	Filippo Volandri	80	3
ESP	Albert Montañés	90	4
BRA	Rogério Dutra da Silva	95	5
ITA	Simone Bolelli	104	6
ESP	Daniel Gimeno Traver	108	7
ITA	Potito Starace	112	8

• ¹ Rankings are as of August 1, 2012.

The following players received wildcards into the singles main draw:

• Alessio di Mauro
• Stefano Galvani
• Nicolás Massú
• Walter Trusendi

The following players received entry from the qualifying draw:

• Claudio Grassi
• Guillermo Hormazábal
• Miliaan Niesten
• Stéphane Robert

• Martin Kližan def. Simone Bolelli, 6–3, 6–1^[1]

• Lukáš Dlouhý / Michal Mertiňák def. Stefano Ianni / Matteo Viola, 2–6, 7–6^(7–3), [11–9]

• Official Website
• ITF Search Archived 2010-02-12 at the Wayback Machine
• ATP official site