Javier Sánchez defeated Guillermo Pérez Roldán 6–2, 7–6 to win the 1988 Buenos Aires Grand Prix singles competition. Perez-Roldan was the defending champion.

	Semifinals							Final
	1	Guillermo Pérez Roldán	6	7
	3	Alberto Mancini	3	6
								1	Guillermo Pérez Roldán	2	6
								7	Javier Sánchez	6	7
		Juan Aguilera	4	0
	7	Javier Sánchez	6	6

	First round							Second round							Quarterfinals							Semifinals
	1	G Pérez Roldán	6	6
		C Allgårdh	3	1				1	G Pérez Roldán	6	6
		P Rebolledo	6	2	3			Q	J Clavet	1	2
	Q	J Clavet	4	6	6										1	G Pérez Roldán	6	6
		R Argüello	6	6												R Argüello	3	1
		F Yunis	4	2					R Argüello	6	7
	WC	M Stringari	7	6	6			WC	M Stringari	3	6
	8	R Viver	6	7	4																	1	G Pérez Roldán	6	7
	3	A Mancini	6	6																		3	A Mancini	3	6
		J Daher	4	1				3	A Mancini	7	6
	Q	F Clavet	6	6				Q	F Clavet	5	2
	WC	G Garetto	2	0											3	A Mancini	6	6
	Q	F Roig	6	6											5	E Bengoechea	3	4
		C Miniussi	4	1				Q	F Roig	1	4
		G Rivas	1	4				5	E Bengoechea	6	6
	5	E Bengoechea	6	6

	First round							Second round							Quarterfinals							Semifinals
	6	F Davín	3	5
		J Aguilera	6	7					J Aguilera	6	6
		R Azar	6	6					R Azar	2	2
	WC	A Garizzio	1	0												J Aguilera	6	6
		J Frana	4	7	3										Q	C Costa	2	4
	Q	C Costa	6	5	6			Q	C Costa	7	6
		M Rackl	4	5				4	H de la Peña	5	2
	4	H de la Peña	6	7																			J Aguilera	4	0
	7	J Sánchez	6	6																		7	J Sánchez	6	6
		M Ingaramo	2	3				7	J Sánchez	7	7
	LL	J Gurfein	4	2					G Giussani	6	6
		G Giussani	6	6											7	J Sánchez	6	3	6
		D Pérez	5	7	6										2	J Berger	3	6	3
		M Hennemann	7	6	2				D Pérez	7	6	2
		F Roese	3	0				2	J Berger	5	7	6
	2	J Berger	6	6

• 1988 ATP Buenos Aires Singles draw