N-acetylneuraminate epimerase (EC 5.1.3.24, sialic acid epimerase, N-acetylneuraminate mutarotase, sialic acid mutarotase, YjhT, NanM) is an enzyme with systematic name N-acetyl-alpha-neuraminate 2-epimerase.[1] This enzyme catalyses the following chemical reaction
- N-acetyl-alpha-neuraminate N-acetyl-beta-neuraminate
Sialoglycoconjugates present in vertebrates are linked exclusively by alpha-linkages.
See also
References
- ^ Severi E, Müller A, Potts JR, Leech A, Williamson D, Wilson KS, Thomas GH (February 2008). "Sialic acid mutarotation is catalyzed by the Escherichia coli beta-propeller protein YjhT". The Journal of Biological Chemistry. 283 (8): 4841–9. doi:10.1074/jbc.M707822200. PMID 18063573.
External links
- N-acetylneuraminate+epimerase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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