First National Bank may refer to:

• First National Bank (Lebanon)

• First National Bank (Namibia)

• Dai-Ichi Bank, formerly First National Bank (第一国立銀行, Dai'ichi Kokuritsu Ginkō)

• First National Bank (South Africa)

• First National Bank of Florida
• First National Bank of Layton, Utah
• First National Bank of Omaha, Nebraska
• FNB Corporation of Pittsburgh, Pennsylvania

• First Bank of the United States, first private central bank of the United States
• First National Bank of Arizona, became part of First Interstate Bancorp
• First National Bank of Boston, acquired by Fleet Bank and merged into Bank of America
• First National Bank of New York, now part of Citibank
• First National Bank of Oregon, became part of First Interstate Bancorp
• First National Bank of San Francisco, merged with Crocker National Bank
• First National Bank, Hoboken, New Jersey
• First Chicago Bank, formerly First National Bank of Chicago, Illinois
• First Financial Bank, formerly First National Bank of Terre Haute, Indiana
• First Maryland Bancorp, now part of M&T Bank
• First National Bank (Bolivar, Missouri)
• First National Bank (Brooksville, Florida)
• First National Bank (Clinton, Iowa)
• First National Bank (Iowa Falls, Iowa)
• First National Bank (Mount Pleasant, Iowa)
• First National Bank (New Cumberland, West Virginia)
• First National Bank (Philadelphia), Philadelphia, Pennsylvania
• First National Bank of Brooklyn, acquired by Bank of the Manhattan Company and merged into JPMorgan Chase
• First National Bank of Charleroi, Charleroi, Pennsylvania
• First National Bank of Charlotte, Charlotte, North Carolina
• First National Bank of Davenport, Iowa
• First National Bank of Dubuque, merged into US Bancorp
• First National Bank of Long Beach
• First National Bank of Mason City, Mason City, Iowa
• First National Bank of Minneapolis and First National Bank of Saint Paul, Minnesota, now part of US Bank
• First National Bank of Whitestone, acquired by Bank of the Manhattan Company and merged into JPMorgan Chase
• PNC Financial Services, formerly First National Bank of Pittsburgh, Pennsylvania
• Regions Bank, formerly First National Bank of Little Rock, Arkansas
• Seafirst Bank or Seattle-First National Bank; acquired by Bank of America
• Security Pacific Bank, formerly Security-First National Bank of Los Angeles, California
• Southeast Banking Corporation, formerly First National Bank of Miami, Florida
• Wachovia Bank of Georgia, formerly First National Bank of Atlanta, Georgia

• First National Bank Building (disambiguation)
• First Bank (disambiguation)
• First National Bank of Boston v. Bellotti
• All pages with titles beginning with First National Bank