Dubuc or du Buc may refer to:

• Dubuc (electoral district), a provincial electoral district in Quebec, Canada
• Dubuc, Saskatchewan

• Aimée du Buc de Rivéry (1768–?), French heiress
• Alain Dubuc, Canadian journalist
• Alfred Dubuc (1871–1947), member of the Canadian House of Commons
• Jean Dubuc (1888–1958), Major League Baseball pitcher
• Jean Dubuc (politician) (born 1941), Canadian politician
• Jessika Dubuc (born 1983), Canadian synchronized swimmer
• Joseph Dubuc (1840–1914), Canadian lawyer and politician
• Lucien Dubuc (1877–1956), Canadian lawyer, judge and politician
• Luis Dubuc (born 1985), musician from Texas
• Marianne Dubuc (illustrator) (born 1980), Canadian writer and illustrator
• Marianne Dubuc (figure skater) (born 1983), Canadian figure skater
• Maryse Dubuc (born 1977), Canadian comics writer
• Nancy Dubuc, American businesswoman
• Nicole Dubuc (born 1978), American writer
• Pierre Dubuc (born 1947), Canadian editor, founder of L'aut'journal
• Roger Dubuc [fr], French tennis player
• Louis-François Dubuc [fr] (1759–1827), French colonial administrator