2-Chloro-m-cresol is a chlorinated cresol. The compound is difficult to synthesise as chlorination of m-cresol yields the para-product (4-chloro-3-methylphenol). Historically synthesis has been achieved via a para-selective nitration, followed by conversion to a diazonium compound and a Sandmeyer reaction to insert the chlorine into the 2-position.[1]
Related compounds
- 4-Chloro-3-methylphenol (PCMC) - similar structure
- 4-Chloro-3,5-dimethylphenol (PCMX) - similar structure
References
- ^ Huston, Ralph C.; Chen, Philip S. (October 1933). "The Chloro Derivatives of m-Cresol". Journal of the American Chemical Society. 55 (10): 4214–4218. doi:10.1021/ja01337a056.
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