Bissonnet or Bissonnette is a surname. Notable people with the surname include:

• Alfred Pike Bissonnet (1914–1979), Canadian diplomat
• Michel Bissonnet (born 1942), Canadian politician, Speaker of the Quebec National Assembly
• Bissonnet Street in Houston, Texas, USA

• Alexandre Bissonnette (born 1989), Canadian mass murderer
• André Bissonnette (born 1945), Canadian businessman and politician
• Anik Bissonnette (born 1962), Canadian dancer
• Bernard Bissonnette (1898–1964), lawyer, merchant, educator, judge and political figure in Quebec
• Father Bernard Bissonnette, central figure in the Bridgeport child abuse scandal
• Big Bill Bissonnette (1937–2018), American jazz trombonist and producer
• J.-Eugène Bissonnette (1892–1980), Canadian politician and physician
• Gaétan Bissonnette (born 1958), Canadian murderer of actress Denise Morelle
• Joel Bissonnette, American actor
• Lise Bissonnette (born 1945), Canadian writer
• Matt Bissonnette (disambiguation), several people
• Michael D. Bissonnette, American politician
• Paul Bissonnette (born 1985), Canadian ice hockey player
• Pierre-André Bissonnette (died 1989), Canadian diplomat

• Bissonette
• Bisson