The 2018 Los Cabos Open (also known as the Abierto Mexicano de Tenis Mifel presentado por Cinemex for sponsorship reasons) was an ATP tennis tournament played on outdoor hard courts. It was the 3rd edition of the Los Cabos Open, and part of the ATP World Tour 250 series of the 2018 ATP World Tour. It took place in Los Cabos, Mexico from July 30 through August 5, 2018.

Country	Player	Rank1	Seed
ARG	Juan Martín del Potro	4	1
ITA	Fabio Fognini	14	2
BIH	Damir Džumhur	24	3
FRA	Adrian Mannarino	26	4
USA	Sam Querrey	29	5
USA	Ryan Harrison	53	6
USA	Taylor Fritz	65	7
ESP	Feliciano López	66	8

• Rankings are as of July 23, 2018.

The following players received wildcards into the singles main draw:

• Ernesto Escobedo
• Lucas Gómez
• Thanasi Kokkinakis

The following players received entry using a protected ranking into the singles main draw:

• Egor Gerasimov
• Yoshihito Nishioka

The following players received entry from the qualifying draw:

• Marcos Giron
• Prajnesh Gunneswaran
• Takanyi Garanganga
• Mohamed Safwat

The following player received entry as a lucky loser:

• Daniel Elahi Galán

Before the tournament

• Matthew Ebden → replaced by Marcelo Arévalo
• Ryan Harrison → replaced by Daniel Elahi Galán
• Filip Krajinović → replaced by Egor Gerasimov
• John Millman → replaced by Bernard Tomic
• Jack Sock → replaced by Quentin Halys

Country	Player	Country	Player	Rank1	Seed
MEX	Santiago González	ESP	David Marrero	103	1
ISR	Jonathan Erlich	GBR	Joe Salisbury	113	2
ESA	Marcelo Arévalo	MEX	Miguel Ángel Reyes-Varela	118	3
MON	Romain Arneodo	USA	Nicholas Monroe	141	4

• Rankings are as of July 23, 2018.

The following pairs received wildcards into the doubles main draw:

• Lucas Gómez / Luis Patiño
• Manuel Sánchez / Bernard Tomic

• Fabio Fognini def. Juan Martín del Potro, 6–4, 6–2

• Marcelo Arévalo / Miguel Ángel Reyes-Varela def. Taylor Fritz / Thanasi Kokkinakis, 6–4, 6–4

• Official website