A split personality, or dissociative identity disorder, is a mental health condition.

Split Personality or Split Personalities may refer to:

• Split Personality (Cassidy album), 2004
• Split Personality (All-4-One album), a 2004 album released by the R&B group All-4-One
• Split Personality, a 2006 album by Mila J
• Split Personalities (album), by 12 Rods, 1998
• "Split Personality", a song by UTFO from the 1986 album Skeezer Pleezer
• "Split Personality", a song by Pink from the 2000 album Can't Take Me Home

• "Split Personalities", Stretch Armstrong and the Flex Fighters season 2, episode 6 (2018)
• "Split Personalities", Telenovela episode 9 (2016)
• "Split Personalities", The Spooktacular New Adventures of Casper season 2, episode 4b (1996)
• "Split Personality", Land of the Lost season 2, episode 12 (1975)
• "Split Personality", Phineas and Ferb season 2, episode 61 (2010)
• "Split Personality", Tales from the Crypt season 4, episode 11 (1992)
• "Split Personality", The Love Boat season 4, episode 19b (1981)
• "Split Personality", The Mask: Animated Series season 1, episode 15 (1995)
• "The Split Personality", The Flintstones season 1, episode 5 (1960)

• Split Personality, a 1959 American game show hosted by Tom Poston
• Split Personality (game show), a 1967 Australian television series

• Split Personalities (video game), 1986

• Multiple personality (disambiguation)