Robert or Bob Hoffman may refer to:

• Robert Hoffman (actor) (born 1980), American actor
• Bob Hoffman (basketball) (born 1957), American basketball coach
• Robert Hoffman (businessman) (1947–2006), American businessman
• Bob Hoffman (American football) (1917–2005), American football player
• Bob Hoffman (sports promoter) (1898–1985), American promoter and entrepreneur of physical culture
• Bobby Hoffman (born 1966), martial arts fighter
• Robert Hoffman (Jericho)
• Robert Hoffmann (1939–2022), Austrian actor and model
• Robert A. Hoffmann, United States Air Force general