Padang Besar may refer to:

• Padang Besar, Malaysia, a town on the Malaysian side of the Malaysia-Thailand border
• Padang Besar, Thailand, a town on the Thai side of the Malaysia-Thailand border

• Padang Besar railway station, a railway station in Padang Besar, Malaysia which is the railway border crossing between Malaysia and Thailand
• Padang Besar (Thai) railway station, a minor railway station in Padang Besar, Thailand

• Padang Besar (federal constituency), a voting district or constituency of the Dewan Rakyat of the Malaysian Parliament

• Padang Basar, a village in North Amuntai district, North Hulu Sungai regency, South Kalimantan, Indonesia

• Padang Besar, a 2012 Thai film known in English as I Carried You Home